Tongda Xu Selected Research

Sarcoplasmic Reticulum Calcium-Transporting ATPases

1/2021	SERCA2a ameliorates cardiomyocyte T-tubule remodeling via the calpain/JPH2 pathway to improve cardiac function in myocardial ischemia/reperfusion mice.
1/2015	Luteolin Exerts Cardioprotective Effects through Improving Sarcoplasmic Reticulum Ca(2+)-ATPase Activity in Rats during Ischemia/Reperfusion In Vivo.
1/2013	ERK/PP1a/PLB/SERCA2a and JNK pathways are involved in luteolin-mediated protection of rat hearts and cardiomyocytes following ischemia/reperfusion.

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Tongda Xu Research Topics

Disease

11	Ischemia 01/2021 - 11/2011
8	Myocardial Infarction 01/2022 - 06/2013
6	Heart Failure 06/2021 - 01/2016
5	Reperfusion Injury 01/2022 - 11/2011
4	Myocardial Ischemia (Ischemic Heart Diseases) 01/2022 - 01/2016
3	Infarction (Infarctions) 01/2021 - 01/2013
3	Cardiovascular Diseases (Cardiovascular Disease) 11/2020 - 12/2012
2	Inflammation (Inflammations) 10/2021 - 01/2014
2	Wounds and Injuries (Trauma) 01/2020 - 01/2015
1	Infections 01/2022
1	Non-ST Elevated Myocardial Infarction 01/2022
1	Coronary Disease (Coronary Heart Disease) 01/2022
1	Thrombosis (Thrombus) 01/2022
1	COVID-19 10/2021
1	Brain Injuries (Brain Injury) 01/2021
1	Neuroinflammatory Diseases 01/2021
1	Brain Diseases (Brain Disorder) 01/2021
1	Gliosis 01/2021
1	Hemorrhage 11/2020
1	Acute Coronary Syndrome 11/2020
1	Neoplasms (Cancer) 03/2019
1	Hypertrophy 01/2019
1	Insulin Resistance 01/2016
1	Hypoxia (Hypoxemia) 01/2016
1	Fibrosis (Cirrhosis) 01/2015
1	Hyperplasia 01/2014
1	Atherosclerosis 01/2014
1	Left Ventricular Dysfunction 06/2013
1	Diabetes Mellitus 12/2012
1	Coronary Restenosis 12/2012
1	Neointima 12/2012
1	Necrosis 11/2011

Drug/Important Bio-Agent (IBA)

9	LuteolinIBA 01/2018 - 12/2012
4	salvianolic acid AIBA 03/2019 - 11/2011
4	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2016 - 01/2013
3	Neprilysin (Neutral Endopeptidase)IBA 06/2021 - 01/2019
3	Angiotensin Receptors (Angiotensin II Receptor)IBA 06/2021 - 01/2019
3	Sarcoplasmic Reticulum Calcium-Transporting ATPasesIBA 01/2021 - 01/2013
3	Proteins (Proteins, Gene)FDA Link 11/2020 - 01/2018
3	Dobutamine FDA LinkGeneric 11/2016 - 06/2013
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021 - 01/2019
2	Angiotensin Receptor AntagonistsIBA 01/2021 - 01/2019
2	Adenosine Triphosphatases (ATPase)IBA 01/2017 - 01/2017
2	pyrazolanthroneIBA 01/2016 - 01/2013
2	Caspase 3 (Caspase-3)IBA 01/2016 - 11/2011
2	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 01/2014 - 01/2013
1	Hemoglobins (Hemoglobin)IBA 01/2022
1	Small Interfering RNA (siRNA)IBA 01/2022
1	Troponin IIBA 01/2022
1	CalciumIBA 01/2022
1	Triglycerides (Triacylglycerol)IBA 01/2022
1	Estrogens (Estrogen)FDA Link 01/2022
1	ReninIBA 10/2021
1	AngiotensinsIBA 10/2021
1	AldosteroneIBA 10/2021
1	Mineralocorticoid Receptor AntagonistsIBA 01/2021
1	phytobacteriomycin (PBM)IBA 01/2021
1	CalpainIBA 01/2021
1	TicagrelorIBA 11/2020
1	Biological ProductsIBA 11/2020
1	Clopidogrel (Plavix)FDA Link 11/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	ethyleneIBA 01/2020
1	Indoleacetic Acids (Auxin)IBA 01/2020
1	Abscisic AcidIBA 01/2020
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2020
1	Carrier Proteins (Binding Protein)IBA 01/2020
1	LipidsIBA 03/2019
1	Enalapril FDA LinkGeneric 01/2019
1	sacubitril and valsartan sodium hydrate drug combinationIBA 01/2019
1	Lysine (L-Lysine)FDA Link 01/2018
1	p38 Mitogen-Activated Protein KinasesIBA 01/2017
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2016
1	JNK Mitogen-Activated Protein KinasesIBA 01/2016
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 01/2016
1	Sodium-Calcium ExchangerIBA 01/2016
1	Phosphotransferases (Kinase)IBA 01/2015
1	Angiotensin IIIBA 01/2015
1	benzimidazoleIBA 01/2015
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2014
1	NF-kappa B (NF-kB)IBA 01/2014
1	LipopolysaccharidesIBA 01/2014
1	Interleukin-1 (Interleukin 1)IBA 01/2014
1	Toll-Like Receptor 4IBA 01/2014
1	IsotopesIBA 06/2013
1	phospholambanIBA 01/2013
1	FlavonoidsIBA 01/2013
1	DNA (Deoxyribonucleic Acid)IBA 12/2012

Therapy/Procedure

2	Therapeutics 01/2022 - 01/2014
2	Percutaneous Coronary Intervention 03/2019 - 12/2012
1	Ovariectomy (Oophorectomy) 01/2022
1	Ischemic Postconditioning 01/2022
1	Drug Therapy (Chemotherapy) 01/2021
1	Low-Level Light Therapy (LLLT) 01/2021
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 03/2019
1	Thrombolytic Therapy 03/2019